Since 2018, treatment with two instead of three active substances is available. For years, it was thought that three active substances were necessary to suppress and maintain suppression of the virus. Recent research shows that in specific cases, two active substances are also sufficient to suppress the virus. Taking one less active substance lowers the risk of side effects.
The effectiveness of HIV medication is determined by measuring viral load. Viral load or burden is the number of virus particles present in the blood.